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ProductsBack/Thrombin antibody

Thrombin antibody

GTX101270

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetF2

Overview

Supplier
GeneTex
Product Name
Thrombin antibody
Delivery Days Customer
9
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID2147
Target name
F2
Target description
coagulation factor II, thrombin
Target synonyms
PT, RPRGL2, THPH1, prothrombin, prepro-coagulation factor II, prothrombin B-chain, thrombin factor II
Host
Rabbit
Isotype
IgG
Protein IDP00734
Protein Name
Prothrombin
Scientific Description
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Yang F, Wei Y, Han D, et al. Interaction with CD68 and Regulation of GAS6 Expression by Endosialin in Fibroblasts Drives Recruitment and Polarization of Macrophages in Hepatocellular Carcinoma. Cancer Res. 2020,80(18):3892-3905. doi: 10.1158/0008-5472.CAN-19-2691
Read this paper
Lin SW, Chuang YC, Lin YS, et al. Dengue virus nonstructural protein NS1 binds to prothrombin/thrombin and inhibits prothrombin activation. J Infect. 2012,64(3):325-34. doi: 10.1016/j.jinf.2011.11.023
Read this paper

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