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IHC-P analysis of human placenta sections using GTX26311 Collagen IV[COL-94] antibody at 1:500.
IHC-P analysis of human placenta sections using GTX26311 Collagen IV[COL-94] antibody at 1:500.
IHC-P analysis of human placenta sections using GTX26311 Collagen IV[COL-94] antibody at 1:500.

Collagen IV antibody [COL-94]

GTX26311
GeneTex
ApplicationsDot Blot, Electron Microscopy, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCOL4A1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Collagen IV antibody [COL-94]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Using immunohistochemical staining of basal laminae, the antibody recognizes an epitope located on the α1 and/or α2 chains of human collagen type IV. The antibody shows reactivity with native primate collagen type IV in ELISA and dot blot assay.
  • Application Supplier Note
    IHC-P: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Dot Blot, Electron Microscopy, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    COL-94
  • Conjugate
    Unconjugated
  • Gene ID1282
  • Target name
    COL4A1
  • Target description
    collagen type IV alpha 1 chain
  • Target synonyms
    arresten; BSVD; BSVD1; COL4A1 NC1 domain; COL4A1s; collagen alpha-1(IV) chain; collagen IV, alpha-1 polypeptide; collagen of basement membrane, alpha-1 chain; PADMAL; RATOR
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP02462
  • Protein Name
    Collagen alpha-1(IV) chain
  • Scientific Description
    Collagen IV is a major constituent of the basement membranes along with laminins and enactins. It is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio . It can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Heterogeneous distribution of trastuzumab in HER2-positive xenografts and metastases: role of the tumor microenvironment. Baker JHE et al., 2018 Oct, Clin Exp Metastasis
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  • MicroRNA-29a mitigation of endoplasmic reticulum and autophagy aberrance counteracts in obstructive jaundice-induced fibrosis in mice. Huang YH et al., 2018 Jan, Exp Biol Med (Maywood)
    Read more
  • Autologous Adipose-Derived Tissue Matrix Part I: Biologic Characteristics. Schendel SA, 2017 Oct 1, Aesthet Surg J
    Read more
  • Stiffened Extracellular Matrix and Signaling from Stromal Fibroblasts via Osteoprotegerin Regulate Tumor Cell Invasion in a 3-D Tumor in Situ Model. McLane JS et al., 2016 Dec, Cancer Microenviron
    Read more