
Western blot (WB) analysis of Cox-2 pAb at 1:500 dilution. Lane1:Hela whole cell lysate treated with LPS. Lane2:Jurkat whole cell lysate treated with LPS. Lane3:Raw264.7 whole cell lysate treated with LPS. Lane3:Rat lung tissue lysate
COX2 antibody
GTX60935
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPTGS2
Overview
- SupplierGeneTex
- Product NameCOX2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000, IHC: 1:50-1:200, IF: 1:50-1:200
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5743
- Target namePTGS2
- Target descriptionprostaglandin-endoperoxide synthase 2
- Target synonymsCOX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2, prostaglandin G/H synthase 2, PGH synthase 2, PHS II, cyclooxygenase 2, cyclooxygenase 2b, prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- HostRabbit
- IsotypeIgG
- Protein IDP35354
- Protein NameProstaglandin G/H synthase 2
- Scientific DescriptionProstaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161
References
- Irf7 regulates the expression of Srg3 and ferroptosis axis aggravated sepsis-induced acute lung injury.Read this paper
- DUSP2 inhibits the progression of lupus nephritis in mice by regulating the STAT3 pathway.Read this paper
- TRPM7 promotes lipopolysaccharide-induced inflammatory dysfunction in renal tubular epithelial cells. Sun Y et al., 2022 Jul, Immun Inflamm DisRead this paper
- Ginsenoside Rh2 Ameliorates Lipopolysaccharide-Induced Acute Lung Injury by Regulating the TLR4/PI3K/Akt/mTOR, Raf-1/MEK/ERK, and Keap1/Nrf2/HO-1 Signaling Pathways in Mice. Hsieh YH et al., 2018 Sep 1, NutrientsRead this paper







![Untreated (–) and treated (+) THP-1 whole cell extract (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with COX2 antibody [C3], C-term (GTX100656) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.](https://www.genetex.com/upload/website/prouct_img/normal/GTX100656/GTX100656_43222_20230203_WB_treatment_PMA_LPS_23020621_417.webp)

