Bio-Connect

COX4 antibody

Research Use Only
GTX114330
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCOX4I1
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    COX4 antibody
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.42 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1327
  • Target name
    COX4I1
  • Target description
    cytochrome c oxidase subunit 4I1
  • Target synonyms
    COX IV-1; COX4; COX4-1; COXIV; COXIV-1; cytochrome c oxidase polypeptide IV; cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit IV; MC4DN16
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3 of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

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  • Altered Insulin Receptor Substrate 1 Phosphorylation in Blood Neuron-Derived Extracellular Vesicles From Patients With Parkinsons Disease. Chou SY et al., 2020, Front Cell Dev Biol
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  • Nrf2/HO-1 mediates the neuroprotective effects of pramipexole by attenuating oxidative damage and mitochondrial perturbation after traumatic brain injury in rats. Salman M et al., 2020 Aug 19, Dis Model Mech
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  • Seizure-induced impairment in neuronal ketogenesis: Role of zinc-alpha2-glycoprotein in mitochondria. Tan C et al., 2020 Jun, J Cell Mol Med
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  • The short variant of optic atrophy 1 (OPA1) improves cell survival under oxidative stress. Lee H et al., 2020 May 8, J Biol Chem
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  • Total glucosides of paeony decreases apoptosis of hepatocytes and inhibits maturation of dendritic cells in autoimmune hepatitis. Shen M et al., 2020 Apr, Biomed Pharmacother
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  • Mitochondrial Transfer of Whartons Jelly Mesenchymal Stem Cells Eliminates Mutation Burden and Rescues Mitochondrial Bioenergetics in Rotenone-Stressed MELAS Fibroblasts. Lin TK et al., 2019, Oxid Med Cell Longev
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  • Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling. Lu CC et al., 2019 Apr, Int J Oncol
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