CPEB1 Antibody

Cusabio

CPEB1 Antibody

20

ELISA

Research Use Only

Polyclonal

Unconjugated

CPEB1

cytoplasmic polyadenylation element binding protein 1

CPEB; CPEB-1; CPE-binding protein 1; CPE-BP1; cytoplasmic polyadenylation element-binding protein 1; h-CPEB; hCPEB-1

Rabbit

IgG

Cytoplasmic polyadenylation element-binding protein 1

Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5-UUUUUAU-3) within the mRNA 3-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.

-20°C or -80°C

12352203