CRLF2 antibody [9T2]

GeneTex

CRLF2 antibody [9T2]

9

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

9T2

500 ug/ml

Unconjugated

CRLF2

cytokine receptor like factor 2

CRL2; CRLF2Y; cytokine receptor CRL2 precusor; cytokine receptor-like factor 2; IL-XR; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin receptor; TSLP receptor; TSLPR

Mouse

IgG1

Cytokine receptor-like factor 2

This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

Human

-20°C or -80°C,2°C to 8°C

12352203