CRLF2 antibody [AT4E7]

GeneTex

CRLF2 antibody [AT4E7]

9

The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:5000. Recommended starting dilution is 1:1000.

Western Blot, ELISA

Research Use Only

Monoclonal

AT4E7

1 mg/ml

Unconjugated

CRLF2

cytokine receptor like factor 2

CRL2; CRLF2Y; cytokine receptor CRL2 precusor; cytokine receptor-like factor 2; IL-XR; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin receptor; TSLP receptor; TSLPR

Mouse

IgG2a

Cytokine receptor-like factor 2

This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

Human

-20°C or -80°C,2°C to 8°C

12352203