CSE1L antibody [GT729]

GeneTex

CSE1L antibody [GT729]

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

GT729

1 mg/ml

Unconjugated

CSE1L

chromosome segregation 1 like

CAS; cellular apoptosis susceptibility protein; chromosome segregation 1-like protein; CSE1; CSE1 chromosome segregation 1-like; epididymis secretory sperm binding protein; exp2; exportin-2; importin-alpha re-exporter; XPO2

Mouse

IgG2a

Exportin-2

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203