CSE1L antibody detects CSE1L protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: CSE1L stained by CSE1L antibody (GTX103005) diluted at 1:1500. Red: phalloidin, a cytoskeleton marker, diluted at 1:200. Scale bar= 10 μm.

CSE1L antibody

GTX103005

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetCSE1L

Overview

Supplier
GeneTex
Product Name
CSE1L antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:1000-1:20000. ICC/IF: 1:100-1:2000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.4 mg/ml
Conjugate
Unconjugated
Gene ID1434
Target name
CSE1L
Target description
chromosome segregation 1 like
Target synonyms
CAS, CSE1, XPO2, exportin-2, BCR/ABL fusion protein, BCR/ABL1 fusion, CSE1 chromosome segregation 1-like, cellular apoptosis susceptibility protein, chromosome segregation 1-like protein, epididymis secretory sperm binding protein, exp2, importin-alpha re-exporter
Host
Rabbit
Isotype
IgG
Protein IDP55060
Protein Name
Exportin-2
Scientific Description
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Wang L, Cai H, Hu Y, et al. A pharmacological probe identifies cystathionine β-synthase as a new negative regulator for ferroptosis. Cell Death Dis. 2018,9(10):1005. doi: 10.1038/s41419-018-1063-2
Read this paper
Tsao HW, Tai TS, Tseng W, et al. Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter. Proc Natl Acad Sci U S A. 2013,110(39):15776-81. doi: 10.1073/pnas.1304343110
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CSE1L antibody

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