WB analysis of PMA-treated HEK293T (A), PMA-treated NIH3T3 (B), PMA-treated H9C2 (C) whole cell lysates using GTX32169 CSK (phospho Ser364) antibody.
WB analysis of PMA-treated HEK293T (A), PMA-treated NIH3T3 (B), PMA-treated H9C2 (C) whole cell lysates using GTX32169 CSK (phospho Ser364) antibody.
CSK (phospho Ser364) antibody
GTX32169
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCSK
Overview
- SupplierGeneTex
- Product NameCSK (phospho Ser364) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1445
- Target nameCSK
- Target descriptionC-terminal Src kinase
- Target synonymsCSK, non-receptor tyrosine kinase; C-Src kinase; c-src tyrosine kinase; protein-tyrosine kinase CYL; tyrosine-protein kinase CSK
- HostRabbit
- IsotypeIgG
- Protein IDP41240
- Protein NameTyrosine-protein kinase CSK
- Scientific DescriptionThe protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203