CTLA4 antibody [BNI3] (APC)
GTX00492-07
ApplicationsFlow Cytometry
Product group Antibodies
TargetCTLA4
Overview
- SupplierGeneTex
- Product NameCTLA4 antibody [BNI3] (APC)
- Delivery Days Customer9
- Application Supplier NoteFACS: 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDBNI3
- ConjugateAPC (Allophycocyanin)
- Gene ID1493
- Target nameCTLA4
- Target descriptioncytotoxic T-lymphocyte associated protein 4
- Target synonymsALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12, cytotoxic T-lymphocyte protein 4, celiac disease 3, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte-associated serine esterase-4, gluten-sensitive enteropathy, insulin-dependent diabetes mellitus 12, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
- HostMouse
- IsotypeIgG2a
- Protein IDP16410
- Protein NameCytotoxic T-lymphocyte protein 4
- Scientific DescriptionThis gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Enhance the anti-renca carcinoma effect of a DNA vaccine targeting G250 gene by co-expression with cytotoxic T-lymphocyte associated antigen-4(CTLA-4). Zhao Y et al., 2017 Jun, Biomed PharmacotherRead more



![FACS analysis of human PBMC stimulated overnight with PMA and Ionomycin stained APC anti-human CD4 antibody, followed by intracellular staining with GTX00492-08 CTLA4 antibody [BNI3] (PE). Right panel : Co-stained with APC anti-human CD4 antibody and GTX00492-08 Left panel : Co-stained with APC anti-human CD4 antibody and PE mouse IgG2a isotype control Antibody amount : 0.5 microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX00492-08/GTX00492-08_20201020_FACS_62_w_23053121_982.webp)
