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CTLA4 antibody [BNI3] (APC)

GTX00492-07
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
TargetCTLA4
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Overview

  • Supplier
    GeneTex
  • Product Name
    CTLA4 antibody [BNI3] (APC)
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    BNI3
  • Conjugate
    APC (Allophycocyanin)
  • Gene ID1493
  • Target name
    CTLA4
  • Target description
    cytotoxic T-lymphocyte associated protein 4
  • Target synonyms
    ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12, cytotoxic T-lymphocyte protein 4, celiac disease 3, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte-associated serine esterase-4, gluten-sensitive enteropathy, insulin-dependent diabetes mellitus 12, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP16410
  • Protein Name
    Cytotoxic T-lymphocyte protein 4
  • Scientific Description
    This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Enhance the anti-renca carcinoma effect of a DNA vaccine targeting G250 gene by co-expression with cytotoxic T-lymphocyte associated antigen-4(CTLA-4). Zhao Y et al., 2017 Jun, Biomed Pharmacother
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