Bio-Connect

Cullin 4a antibody [N1C1]

GTX113876
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Zebra Fish
TargetCUL4A
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cullin 4a antibody [N1C1]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8451
  • Target name
    CUL4A
  • Target description
    cullin 4A
  • Target synonyms
    CUL-4A; cullin-4A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13619
  • Protein Name
    Cullin-4A
  • Scientific Description
    CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]).[supplied by OMIM]
  • Reactivity
    Human, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation. Lanzafame M et al., 2021 Nov 8, Nucleic Acids Res
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  • CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and Leukodystrophy. Fu SJ et al., 2020 May 26, Cells
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  • Nuclear and cytoplasmic WDR-23 isoforms mediate differential effects on GEN-1 and SKN-1 substrates. Spatola BN et al., 2019 Aug 13, Sci Rep
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  • WDR23 regulates NRF2 independently of KEAP1. Lo JY et al., 2017 Apr, PLoS Genet
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  • The Cullin 4A/B-DDB1-Cereblon E3 Ubiquitin Ligase Complex Mediates the Degradation of CLC-1 Chloride Channels. Chen YA et al., 2015 May 29, Sci Rep
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