CXCR7 antibody [C1C2], Internal
GTX100027
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetACKR3
Overview
- SupplierGeneTex
- Product NameCXCR7 antibody [C1C2], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.14 mg/ml
- ConjugateUnconjugated
- Gene ID57007
- Target nameACKR3
- Target descriptionatypical chemokine receptor 3
- Target synonymsatypical chemokine receptor 3; chemokine (C-X-C motif) receptor 7; chemokine orphan receptor 1; CMKOR1; C-X-C chemokine receptor type 7; CXCR7; CXC-R7; CXCR-7; G protein-coupled receptor; GPR159; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; RDC1; RDC-1
- HostRabbit
- IsotypeIgG
- Protein IDP25106
- Protein NameAtypical chemokine receptor 3
- Scientific DescriptionThis gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Human embryonic stem cells secrete macrophage migration inhibitory factor: A novel finding.Read more
- D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling. Song S et al., 2021 Jun, EBioMedicineRead more
- MiR-139 Modulates Cancer Stem Cell Function of Human Breast Cancer through Targeting CXCR4. Cheng CW et al., 2021 May 25, Cancers (Basel)Read more
- Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling. Wei ST et al., 2020 May 4, Cell Death DisRead more
- CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells. Xu T et al., 2019 Oct 31, Cell Death DisRead more
- CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC. Becker JH et al., 2019 Sep 1, Cancer ResRead more
- Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer. Li S et al., 2019 May 15, Cancer ResRead more
- CX Chemokine Receptor 7 Contributes to Survival of KRAS-Mutant Non-Small Cell Lung Cancer upon Loss of Epidermal Growth Factor Receptor. Liu B et al., 2019 Mar 30, Cancers (Basel)Read more
- CXCR7 promotes melanoma tumorigenesis via Src kinase signaling. Xu S et al., 2019 Feb 25, Cell Death DisRead more
- Enzalutamide and CXCR7 inhibitor combination treatment suppresses cell growth and angiogenic signaling in castration-resistant prostate cancer models. Luo Y et al., 2018 May 15, Int J CancerRead more