More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/CXCR7 antibody [C1C2], Internal

CXCR7 antibody [C1C2], Internal

GTX100027
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetACKR3
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    CXCR7 antibody [C1C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.14 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID57007
  • Target name
    ACKR3
  • Target description
    atypical chemokine receptor 3
  • Target synonyms
    CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1, atypical chemokine receptor 3, C-X-C chemokine receptor type 7, G protein-coupled receptor, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, chemokine (C-X-C motif) receptor 7, chemokine orphan receptor 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP25106
  • Protein Name
    Atypical chemokine receptor 3
  • Scientific Description
    This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Wei Y, Zheng X, Huang T, et al. Human embryonic stem cells secrete macrophage migration inhibitory factor: A novel finding. PLoS One. 2023,18(8):e0288281. doi: 10.1371/journal.pone.0288281
    Read this paper
  • Song S, Liu B, Habibie H, et al. D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling. EBioMedicine. 2021,68:103412. doi: 10.1016/j.ebiom.2021.103412
    Read this paper
  • Cheng CW, Liao WL, Chen PM, et al. MiR-139 Modulates Cancer Stem Cell Function of Human Breast Cancer through Targeting CXCR4. Cancers (Basel). 2021,13(11). doi: 10.3390/cancers13112582
    Read this paper
  • Wei ST, Huang YC, Hsieh ML, et al. Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling. Cell Death Dis. 2020,11(5):307. doi: 10.1038/s41419-020-2512-2
    Read this paper
  • Xu T, Yu X, Deng J, et al. CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells. Cell Death Dis. 2019,10(11):825. doi: 10.1038/s41419-019-2052-9
    Read this paper
  • Becker JH, Gao Y, Soucheray M, et al. CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC. Cancer Res. 2019,79(17):4439-4452. doi: 10.1158/0008-5472.CAN-19-0024
    Read this paper
  • Li S, Fong KW, Gritsina G, et al. Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer. Cancer Res. 2019,79(10):2580-2592. doi: 10.1158/0008-5472.CAN-18-2812
    Read this paper
  • Liu B, Song S, Setroikromo R, et al. CX Chemokine Receptor 7 Contributes to Survival of KRAS-Mutant Non-Small Cell Lung Cancer upon Loss of Epidermal Growth Factor Receptor. Cancers (Basel). 2019,11(4). doi: 10.3390/cancers11040455
    Read this paper
  • Xu S, Tang J, Wang C, et al. CXCR7 promotes melanoma tumorigenesis via Src kinase signaling. Cell Death Dis. 2019,10(3):191. doi: 10.1038/s41419-019-1442-3
    Read this paper
  • Luo Y, Azad AK, Karanika S, et al. Enzalutamide and CXCR7 inhibitor combination treatment suppresses cell growth and angiogenic signaling in castration-resistant prostate cancer models. Int J Cancer. 2018,142(10):2163-2174. doi: 10.1002/ijc.31237
    Read this paper

Datasheet

Download Datasheet

FAQ

Go to our frequently asked questions

Related products

Product group Antibodies
Assay Genie
CXCR7 Monoclonal AntibodyCAB8991
TargetACKR3
  • SizePrice
Anti-ACKR3 Antibody
Product group Antibodies
Antibodies.com
Anti-ACKR3 AntibodyA46576
ApplicationsImmunoHistoChemistry
  • SizePrice
Figure 1. Western blot analysis of GPCR RDC1/CXCR-7/ACKR3 using anti-GPCR RDC1/CXCR-7/ACKR3 antibody (A02656-2). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: human RT4 whole cell lysates, Lane 2: human Hela whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-GPCR RDC1/CXCR-7/ACKR3 antigen affinity purified polyclonal antibody (Catalog # A02656-2) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for GPCR RDC1/CXCR-7/ACKR3 at approximately 41 kDa. The expected band size for GPCR RDC1/CXCR-7/ACKR3 is at 41 kDa.
Product group Antibodies
Boster Bio
Anti-GPCR RDC1/CXCR-7/ACKR3 Antibody Picoband(r)A02656-2-CARRIER-FREE
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry
TargetACKR3
  • SizePrice
Product group Antibodies
RayBiotech
Anti-ACKR3 Antibody144-12712
ApplicationsWestern Blot
TargetACKR3
  • SizePrice
Product group Antibodies
Everest Biotech
Goat anti-CXCR7 / RDC1EB12777
ApplicationsWestern Blot, ELISA
TargetACKR3
  • SizePrice
IHC-P analysis of baboon small intestine tissue using GTX82935 CXCR7 antibody. Dilution : 1:100
Product group Antibodies
References
GeneTex
CXCR7 antibodyGTX82935
ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetACKR3
  • SizePrice
Product group Antibodies
GeneTex
CXCR7 antibody [HL2189]GTX638193
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetACKR3
  • SizePrice
Product group Antibodies
GeneTex
CXCR7 antibody [H342] HistoMAX(tm)GTX641403
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetACKR3
  • SizePrice
Product group Antibodies
LifeSpan BioSciences
ACKR3 / CXCR7 AntibodyLS-C747794
ApplicationsWestern Blot
TargetACKR3
  • SizePrice
Formalin-fixed and paraffin embedded rat brain labeled with Anti-CXCR7/RDC1 Polyclonal Antibody, Unconjugated (bs-4897R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
Product group Antibodies
References
Bioss
ACKR3 Polyclonal AntibodyBS-4897R
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetACKR3
  • SizePrice