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ProductsBack/Cyclin A2 antibody

Cyclin A2 antibody

Research Use Only
GTX103042
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Monkey, Mouse, Rat
TargetCCNA2
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Packing Size
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cyclin A2 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    IP/MS validation was supported by references (PMID:30377384)
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.73 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID890
  • Target name
    CCNA2
  • Target description
    cyclin A2
  • Target synonyms
    CCN1; CCNA; cyclin-A; cyclin-A2
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. [provided by RefSeq]
  • Reactivity
    Human, Monkey, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Salviolone from Salvia miltiorrhiza Roots Impairs Cell Cycle Progression, Colony Formation, and Metalloproteinase-2 Activity in A375 Melanoma Cells: Involvement of P21(Cip1/Waf1) Expression and STAT3 Phosphorylation. Zanr V et al., 2022 Jan 20, Int J Mol Sci
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  • Auranofin induces urothelial carcinoma cell death via reactive oxygen species production and synergy with cisplatin. Chen SY et al., 2022 Feb, Oncol Lett
    Read more
  • Inhibition of Protein Synthesis Induced by CHK1 Inhibitors Discriminates Sensitive from Resistant Cancer Cells. Hinds JW et al., 2021 Aug 13, ACS Pharmacol Transl Sci
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  • Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance. Pietilae EA et al., 2021 Jun 23, Nat Commun
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  • Activation of CDC25A phosphatase is limited by CDK2/cyclin A-mediated feedback inhibition. Ditano JP et al., 2021 Jul, Cell Cycle
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  • Reptin/RUVBL2 is required for hepatocyte proliferation in vivo, liver regeneration and homeostasis. Javary J et al., 2021 Jun, Liver Int
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  • CSN1 facilitates proliferation and migration of hepatocellular carcinoma cells by upregulating cyclin A2 expression. Fu H et al., 2021 Jan, Mol Med Rep
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  • Targeting DNA and mutant p53 by a naphthalimide derivative, NA20, exhibits selective inhibition in gastric tumorigenesis by blocking mutant p53-EGFR signaling pathway. Zhang G et al., 2020 Nov 15, Eur J Pharmacol
    Read more
  • Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis. Huang HY et al., 2020 Sep, J Cell Mol Med
    Read more
  • PDZRN3 protects against apoptosis in myoblasts by maintaining cyclin A2 expression. Honda T et al., 2020 Jan 24, Sci Rep
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