Cyclin E antibody [168]
GTX16122
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman, Monkey
TargetCCNE1
Overview
- SupplierGeneTex
- Product NameCyclin E antibody [168]
- Delivery Days Customer9
- Application Supplier NoteIP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 50 kDa. Optimal dilutions/concentrations should be determined by the end user.
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID168
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID898
- Target nameCCNE1
- Target descriptioncyclin E1
- Target synonymsCCNE; G1/S-specific cyclin-E1; pCCNE1
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionCyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
- ReactivityHuman, Monkey
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203