Cyclin E antibody
GTX22094
ApplicationsImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetCCNE1
Overview
- SupplierGeneTex
- Product NameCyclin E antibody
- Delivery Days Customer9
- Antibody SpecificityNo reaction was observed against other related cyclins.
- Application Supplier NoteWB: 1:2000-1:10000. IP: 1:100. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID898
- Target nameCCNE1
- Target descriptioncyclin E1
- Target synonymsCCNE; G1/S-specific cyclin-E1; pCCNE1
- HostRabbit
- IsotypeIgG
- Protein IDP24864
- Protein NameG1/S-specific cyclin-E1
- Scientific DescriptionCyclin E is a regulatory subunit of cdk 2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203