Cyclin E antibody

GeneTex

Cyclin E antibody

9

WB: 1:2000-1:10000. IP: 1:100. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

CCNE1

cyclin E1

CCNE; G1/S-specific cyclin-E1; pCCNE1

Rabbit

IgG

G1/S-specific cyclin-E1

Cyclin E is a regulatory subunit of cdk 2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

-20°C or -80°C,2°C to 8°C

12352203