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Cyclin E antibody

GTX22094
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetCCNE1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cyclin E antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    No reaction was observed against other related cyclins.
  • Application Supplier Note
    WB: 1:2000-1:10000. IP: 1:100. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID898
  • Target name
    CCNE1
  • Target description
    cyclin E1
  • Target synonyms
    CCNE; G1/S-specific cyclin-E1; pCCNE1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP24864
  • Protein Name
    G1/S-specific cyclin-E1
  • Scientific Description
    Cyclin E is a regulatory subunit of cdk 2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203