
WB analysis of various sample using GTX56293 CYP11A1 antibody. Lane 1 : HEK293T cell lysate Lane 2 : HeLa cell lysate Lane 3 : H460 cell lysate Lane 4 : Mouse lung tissue lysate
CYP11A1 antibody
GTX56293
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCYP11A1
Overview
- SupplierGeneTex
- Product NameCYP11A1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. ICC/IF: 1:100 - 1:500. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1583
- Target nameCYP11A1
- Target descriptioncytochrome P450 family 11 subfamily A member 1
- Target synonymsCYP11A, CYPXIA1, P450SCC, cholesterol side-chain cleavage enzyme, mitochondrial, cholesterol 20-22 desmolase, cholesterol monooxygenase (side-chain cleaving), cytochrome P450 11A1, cytochrome P450 family 11 subfamily A polypeptide 1, cytochrome P450(scc), cytochrome P450, subfamily XIA (cholesterol side chain cleavage), steroid 20-22-lyase
- HostRabbit
- IsotypeIgG
- Protein IDP05108
- Protein NameCholesterol side-chain cleavage enzyme, mitochondrial
- Scientific DescriptionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161
References
- Association Between 17beta-Estradiol Receptors and Nitric Oxide Signaling Augments High-Altitude Adaptation of Ladakhi Highlanders. Pooja et al., 2021 Jun, High Alt Med BiolRead this paper
- Transplantation of encapsulated human Leydig-like cells: A novel option for the treatment of testosterone deficiency. Feng X et al., 2021 Jan 1, Mol Cell EndocrinolRead this paper
- Estrogen receptor (ESR1 and ESR2)-mediated activation of eNOS-NO-cGMP pathway facilitates high altitude acclimatization. Pooja et al., 2020 Sep 1, Nitric OxideRead this paper
- FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. Zhang C et al., 2020 Jan 20, Aging (Albany NY)Read this paper
- Alteration in iron efflux affects male sex hormone testosterone biosynthesis in a diet-induced obese rat model. Kurniawan AL et al., 2019 Jul 17, Food FunctRead this paper
- Establishing a nonlethal and efficient mouse model of male gonadotoxicity by intraperitoneal busulfan injection. Xie Y et al., 2019 Jun 7, Asian J AndrolRead this paper








