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WB analysis of various sample using GTX56293 CYP11A1 antibody. Lane 1 : HEK293T cell lysate Lane 2 : HeLa cell lysate Lane 3 : H460 cell lysate Lane 4 : Mouse lung tissue lysate
WB analysis of various sample using GTX56293 CYP11A1 antibody. Lane 1 : HEK293T cell lysate Lane 2 : HeLa cell lysate Lane 3 : H460 cell lysate Lane 4 : Mouse lung tissue lysate
WB analysis of various sample using GTX56293 CYP11A1 antibody. Lane 1 : HEK293T cell lysate Lane 2 : HeLa cell lysate Lane 3 : H460 cell lysate Lane 4 : Mouse lung tissue lysate

CYP11A1 antibody

GTX56293
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCYP11A1
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Overview

  • Supplier
    GeneTex
  • Product Name
    CYP11A1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:1000. ICC/IF: 1:100 - 1:500. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1583
  • Target name
    CYP11A1
  • Target description
    cytochrome P450 family 11 subfamily A member 1
  • Target synonyms
    CYP11A, CYPXIA1, P450SCC, cholesterol side-chain cleavage enzyme, mitochondrial, cholesterol 20-22 desmolase, cholesterol monooxygenase (side-chain cleaving), cytochrome P450 11A1, cytochrome P450 family 11 subfamily A polypeptide 1, cytochrome P450(scc), cytochrome P450, subfamily XIA (cholesterol side chain cleavage), steroid 20-22-lyase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05108
  • Protein Name
    Cholesterol side-chain cleavage enzyme, mitochondrial
  • Scientific Description
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    41116161

References

  • Association Between 17beta-Estradiol Receptors and Nitric Oxide Signaling Augments High-Altitude Adaptation of Ladakhi Highlanders. Pooja et al., 2021 Jun, High Alt Med Biol
    Read this paper
  • Transplantation of encapsulated human Leydig-like cells: A novel option for the treatment of testosterone deficiency. Feng X et al., 2021 Jan 1, Mol Cell Endocrinol
    Read this paper
  • Estrogen receptor (ESR1 and ESR2)-mediated activation of eNOS-NO-cGMP pathway facilitates high altitude acclimatization. Pooja et al., 2020 Sep 1, Nitric Oxide
    Read this paper
  • FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. Zhang C et al., 2020 Jan 20, Aging (Albany NY)
    Read this paper
  • Alteration in iron efflux affects male sex hormone testosterone biosynthesis in a diet-induced obese rat model. Kurniawan AL et al., 2019 Jul 17, Food Funct
    Read this paper
  • Establishing a nonlethal and efficient mouse model of male gonadotoxicity by intraperitoneal busulfan injection. Xie Y et al., 2019 Jun 7, Asian J Androl
    Read this paper