CYP17A1 antibody, Internal

GeneTex

CYP17A1 antibody, Internal

7

WB: 0.1-0.3microg/ml. IHC-P: 3-5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

CYP17A1

cytochrome P450 family 17 subfamily A member 1

17-alpha-hydroxyprogesterone aldolase; CPT7; CYP17; CYPXVII; cytochrome P450 17A1; cytochrome p450 XVIIA1; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia; cytochrome P450c17; cytochrome P450-C17; P450C17; S17AH; steroid 17-alpha-hydroxylase/17,20 lyase; steroid 17-alpha-monooxygenase

Goat

IgG

Steroid 17-alpha-hydroxylase/17,20 lyase

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203