ProductsBack/CYR61 antibody [N1C3]

CYR61 antibody [N1C3]

Name: CYR61 antibody [N1C3]
SKU: GTX103669_G10
Availability: BackOrder

GTX103669

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetCCN1

Overview

Supplier
GeneTex
Product Name
CYR61 antibody [N1C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.34 mg/ml
Conjugate
Unconjugated
Gene ID3491
Target name
CCN1
Target description
cellular communication network factor 1
Target synonyms
CYR61, GIG1, IGFBP10, CCN family member 1, IBP-10, IGF-binding protein 10, IGFBP-10, cysteine rich angiogenic inducer 61, cysteine-rich heparin-binding protein 61, cysteine-rich, anigogenic inducer, 61, insulin-like growth factor-binding protein 10, protein CYR61
Host
Rabbit
Isotype
IgG
Protein IDO00622
Protein Name
CCN family member 1
Scientific Description
CYR61 is a secreted, cysteine-rich, heparin-binding protein encoded by a growth factor-inducible immediate-early gene. Acting as an extracellular, matrix-associated signaling molecule, CYR61 promotes the adhesion of endothelial cells through interaction with integrin and augments growth factor-induced DNA synthesis in the same cell type.[supplied by OMIM]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Poli G, Sarchielli E, Guasti D, et al. Human fetal adrenal cells retain age-related stem- and endocrine-differentiation potential in culture. FASEB J. 2019,33(2):2263-2277. doi: 10.1096/fj.201801028RR
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Shih YC, Chen CL, Zhang Y, et al. Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation. Circ Res. 2018,122(8):1052-1068. doi: 10.1161/CIRCRESAHA.117.312130
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Chen MC, Tsai YC, Tseng JH, et al. Simvastatin Inhibits Cell Proliferation and Migration in Human Anaplastic Thyroid Cancer. Int J Mol Sci. 2017,18(12). doi: 10.3390/ijms18122690
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