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ProductsBack/Cytokeratin 8 antibody

Cytokeratin 8 antibody

GTX110311

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetKRT8

Overview

Supplier
GeneTex
Product Name
Cytokeratin 8 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.82 mg/ml
Conjugate
Unconjugated
Gene ID3856
Target name
KRT8
Target description
keratin 8
Target synonyms
CARD2, CK-8, CK8, CYK8, K2C8, K8, KO, keratin, type II cytoskeletal 8, cytokeratin-8, keratin 8, type II, type-II keratin Kb8
Host
Rabbit
Isotype
IgG
Protein IDP05787
Protein Name
Keratin, type II cytoskeletal 8
Scientific Description
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Chen CH, Lin DS, Cheng CW, et al. Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish. Oncotarget. 2014,5(15):6300-11.
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