DAP5 antibody [39C534.1]

GeneTex

DAP5 antibody [39C534.1]

9

WB: 1 - 2 microg/ml. FACS: 1 microg / 106 cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, Western Blot

Research Use Only

Monoclonal

39C534.1

0.5 mg/ml

Unconjugated

EIF4G2

eukaryotic translation initiation factor 4 gamma 2

AAG1; aging-associated protein 1; DAP5; DAP-5; death-associated protein 5; eIF4G 2; eIF-4G 2; eIF-4-gamma 2; eukaryotic translation initiation factor 4 gamma 2; eukaryotic translation initiation factor 4G-like 1; NAT1; P97

Mouse

IgG1

Eukaryotic translation initiation factor 4 gamma 2

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq]

Hamster, Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203