DAP5 antibody

GeneTex

DAP5 antibody

9

WB: 1:500 - 1:1000. ICC/IF: 1:50 - 1:200. IHC-P: 1:100 - 1:200. IP: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

EIF4G2

eukaryotic translation initiation factor 4 gamma 2

AAG1; aging-associated protein 1; DAP5; DAP-5; death-associated protein 5; eIF4G 2; eIF-4G 2; eIF-4-gamma 2; eukaryotic translation initiation factor 4 gamma 2; eukaryotic translation initiation factor 4G-like 1; NAT1; P97

Rabbit

IgG

Eukaryotic translation initiation factor 4 gamma 2

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203