Decorin antibody

Name: Decorin antibody
SKU: GTX101250_G10
Availability: BackOrder

GTX101250

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Rat

TargetDCN

Overview

Supplier
GeneTex
Product Name
Decorin antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID1634
Target name
DCN
Target description
decorin
Target synonyms
CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B, decorin, bone proteoglycan II, dermatan sulphate proteoglycans II, proteoglycan core protein, small leucine-rich protein 1B
Host
Rabbit
Isotype
IgG
Protein IDP07585
Protein Name
Decorin
Scientific Description
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome. [provided by RefSeq]
Reactivity
Human, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Ayvacı H, Koç N, Tarhan N, et al. Decorin expression in tubal ectopic and intrauterine pregnancies. J Gynecol Obstet Hum Reprod. 2021,50(10):102213. doi: 10.1016/j.jogoh.2021.102213
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Wong TH, Chen TY, Tseng KY, et al. Decorin inhibits the insulin-like growth factor I signaling in bone marrow mesenchymal stem cells of aged humans. Aging (Albany NY). 2020,13(1):578-597. doi: 10.18632/aging.202166
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Brauchle E, Kasper J, Daum R, et al. Biomechanical and biomolecular characterization of extracellular matrix structures in human colon carcinomas. Matrix Biol. 2018,68-69:180-193. doi: 10.1016/j.matbio.2018.03.016
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Hinderer S, Sudrow K, Schneider M, et al. Surface functionalization of electrospun scaffolds using recombinant human decorin attracts circulating endothelial progenitor cells. Sci Rep. 2018,8(1):110. doi: 10.1038/s41598-017-18382-y
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Cates JM, Memoli VA, Gonzalez RS. Cell cycle and apoptosis regulatory proteins, proliferative markers, cell signaling molecules, CD209, and decorin immunoreactivity in low-grade myxofibrosarcoma and myxoma. Virchows Arch. 2015,467(2):211-6. doi: 10.1007/s00428-015-1778-8
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Hinderer S, Schesny M, Bayrak A, et al. Engineering of fibrillar decorin matrices for a tissue-engineered trachea. Biomaterials. 2012,33(21):5259-66. doi: 10.1016/j.biomaterials.2012.03.075
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Decorin antibody

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