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ProductsBack/Decorin antibody

Decorin antibody

GTX101250
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Rat
TargetDCN
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Overview

  • Supplier
    GeneTex
  • Product Name
    Decorin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1634
  • Target name
    DCN
  • Target description
    decorin
  • Target synonyms
    bone proteoglycan II; CSCD; decorin; dermatan sulphate proteoglycans II; DSPG2; PG40; PGII; PGS2; proteoglycan core protein; SLRR1B; small leucine-rich protein 1B
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP07585
  • Protein Name
    Decorin
  • Scientific Description
    The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome. [provided by RefSeq]
  • Reactivity
    Human, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Decorin expression in tubal ectopic and intrauterine pregnancies. Ayvaci H et al., 2021 Dec, J Gynecol Obstet Hum Reprod
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  • Decorin inhibits the insulin-like growth factor I signaling in bone marrow mesenchymal stem cells of aged humans. Wong TH et al., 2020 Nov 26, Aging (Albany NY)
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  • Biomechanical and biomolecular characterization of extracellular matrix structures in human colon carcinomas. Brauchle E et al., 2018 Aug, Matrix Biol
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  • Surface functionalization of electrospun scaffolds using recombinant human decorin attracts circulating endothelial progenitor cells. Hinderer S et al., 2018 Jan 8, Sci Rep
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  • Cell cycle and apoptosis regulatory proteins, proliferative markers, cell signaling molecules, CD209, and decorin immunoreactivity in low-grade myxofibrosarcoma and myxoma. Cates JM et al., 2015 Aug, Virchows Arch
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  • Engineering of fibrillar decorin matrices for a tissue-engineered trachea. Hinderer S et al., 2012 Jul, Biomaterials
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