Desmin antibody
GTX103557
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetDES
Overview
- SupplierGeneTex
- Product NameDesmin antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.42 mg/ml
- ConjugateUnconjugated
- Gene ID1674
- Target nameDES
- Target descriptiondesmin
- Target synonymsCDCD3, CSM1, CSM2, LGMD1D, LGMD1E, LGMD2R, desmin, cardiomyopathy, dilated 1F (autosomal dominant), cardiomyopathy, dilated 1I, epididymis secretory sperm binding protein, intermediate filament protein
- HostRabbit
- IsotypeIgG
- Protein IDP17661
- Protein NameDesmin
- Scientific DescriptionThis gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Skelton LA, Ramachandra Rao S, Allen RS, et al. Retinal gliosis and phenotypic diversity of intermediate filament induction and remodeling upon acoustic blast overpressure (ABO) exposure to the rat eye. Exp Eye Res. 2023,234:109585. doi: 10.1016/j.exer.2023.109585Read this paper
- Lee Y, DiMaulo-Milk E, Leslie J, et al. Hematopoietic stem cells temporally transition to thrombopoietin dependence in the fetal liver. Sci Adv. 2022,8(11):eabm7688. doi: 10.1126/sciadv.abm7688Read this paper
- Weber B, Lackner I, Miclau T, et al. Early myocardial damage (EMD) and valvular dysfunction after femur fracture in pigs. Sci Rep. 2021,11(1):8503. doi: 10.1038/s41598-021-86151-zRead this paper
- Lee Y, Leslie J, Yang Y, et al. Hepatic stellate and endothelial cells maintain hematopoietic stem cells in the developing liver. J Exp Med. 2021,218(3). doi: 10.1084/jem.20200882Read this paper
- Lackner I, Weber B, Miclau T, et al. Reaming of femoral fractures with different reaming irrigator aspirator systems shows distinct effects on cardiac function after experimental polytrauma. J Orthop Res. 2020,38(12):2608-2618. doi: 10.1002/jor.24830Read this paper
- Chen YH, Su CC, Deng W, et al. Mitochondrial Akt Signaling Modulated Reprogramming of Somatic Cells. Sci Rep. 2019,9(1):9919. doi: 10.1038/s41598-019-46359-6Read this paper
- Li YK, Li YM, Li Y, et al. CTHRC1 expression in primary biliary cholangitis. J Dig Dis. 2019,20(7):371-376. doi: 10.1111/1751-2980.12791Read this paper
- Foertsch S, Lackner I, Weber B, et al. Sensory contact to the stressor prevents recovery from structural and functional heart damage following psychosocial trauma. Brain Behav Immun. 2019,80:667-677. doi: 10.1016/j.bbi.2019.05.013Read this paper
- Fang CC, Wu CF, Liao YJ, et al. AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage. Sci Rep. 2018,8(1):13802. doi: 10.1038/s41598-018-30800-3Read this paper
- Cargnoni A, Farigu S, Cotti Piccinelli E, et al. Effect of human amniotic epithelial cells on pro-fibrogenic resident hepatic cells in a rat model of liver fibrosis. J Cell Mol Med. 2018,22(2):1202-1213. doi: 10.1111/jcmm.13396Read this paper
![IHC-P analysis of human leiomyoma tissue using GTX17156 Desmin antibody [D33].](https://www.genetex.com/upload/website/prouct_img/normal/GTX17156/GTX17156_20191203_IHC-P_32_w_23060620_543.webp)
![IHC-P analysis of human leiomyoma tissue using GTX20959 Desmin antibody [D33] (ready-to-use).](https://www.genetex.com/upload/website/prouct_img/normal/GTX20959/GTX20959_20191203_IHC-P_80_w_23060620_377.webp)
![IHC-P analysis of human bowel tissue using GTX01930 Desmin antibody [DE-R-11]. Note cytoplasmic staining of smooth muscle containing cells.](https://www.genetex.com/upload/website/prouct_img/normal/GTX01930/GTX01930_20200811_IHC-P_30_w_23053121_101.webp)
![IHC-P analysis of human smooth muscle sarcoma using GTX83146 Desmin antibody [10H7D2].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83146/GTX83146_20170912_IHC-P_w_23061322_145.webp)

![IHC-P analysis of human heart tissue using GTX33613 Desmin antibody [RM234]. Dilution : 1:4000](https://www.genetex.com/upload/website/prouct_img/normal/GTX33613/GTX33613_20200909_IHC-P_224_w_23060800_402.webp)
![IHC-P analysis of human lung tissue using GTX34350 Desmin antibody [1B12]. Negative control (the lower left coner) was secondary antibody only. Antigen retrieval : Sodium citrate pH6.0 was used for antibody retrieval (>98oC, 20min) Dilution : 1:200](https://www.genetex.com/upload/website/prouct_img/normal/GTX34350/GTX34350_20200622_IHC-P_074_w_23060801_386.webp)