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Desmoglein 2 antibody [N1N2], N-term

GTX102508
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetDSG2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Desmoglein 2 antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.36 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1829
  • Target name
    DSG2
  • Target description
    desmoglein 2
  • Target synonyms
    cadherin family member 5; CDHF5; desmoglein-2; HDGC
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ14126
  • Protein Name
    Desmoglein-2
  • Scientific Description
    Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Krueppel-like factor 5 is essential for maintenance of barrier function in mouse colon. Liu Y et al., 2017 Nov 1, Am J Physiol Gastrointest Liver Physiol
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