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Dishevelled 2 antibody [N2C2], Internal

GTX103878
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetDVL2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Dishevelled 2 antibody [N2C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.04 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1856
  • Target name
    DVL2
  • Target description
    dishevelled segment polarity protein 2
  • Target synonyms
    segment polarity protein dishevelled homolog DVL-2, dishevelled 2 (homologous to Drosophila dsh), dishevelled, dsh homolog 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO14641
  • Protein Name
    Segment polarity protein dishevelled homolog DVL-2
  • Scientific Description
    This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The Role of Wnt/beta-Catenin Pathway Mediators in Aortic Valve Stenosis. Khan K et al., 2020, Front Cell Dev Biol
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  • Dishevelled proteins are associated with olfactory sensory neuron presynaptic terminals. Rodriguez-Gil DJ et al., 2013, PLoS One
    Read more