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IHC-P analysis of mouse embryo tissue using GTX60309 DLK1 antibody. Dilution : 1:200
IHC-P analysis of mouse embryo tissue using GTX60309 DLK1 antibody. Dilution : 1:200
IHC-P analysis of mouse embryo tissue using GTX60309 DLK1 antibody. Dilution : 1:200

DLK1 antibody

GTX60309
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat, Sheep
TargetDLK1
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Overview

  • Supplier
    GeneTex
  • Product Name
    DLK1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:300-1000. IHC-P: 1:50-400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8788
  • Target name
    DLK1
  • Target description
    delta like non-canonical Notch ligand 1
  • Target synonyms
    Delta1; delta-like 1 homolog; DLK; DLK-1; FA1; fetal antigen 1; pG2; preadipocyte factor 1; PREF1; Pref-1; protein delta homolog 1; secredeltin; ZOG
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP80370
  • Protein Name
    Protein delta homolog 1
  • Scientific Description
    This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010]
  • Reactivity
    Human, Mouse, Rat, Sheep
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Antimicrobial production by perifollicular dermal preadipocytes is essential to the pathophysiology of acne.
    Read more
  • Skin inflammation activates intestinal stromal fibroblasts and promotes colitis. Dokoshi T et al., 2021 Nov 1, J Clin Invest
    Read more