DNMT1 antibody [N1], N-term
GTX116011
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetDNMT1
Overview
- SupplierGeneTex
- Product NameDNMT1 antibody [N1], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. ICC/IF: 1:100-1:2000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.18 mg/ml
- ConjugateUnconjugated
- Gene ID1786
- Target nameDNMT1
- Target descriptionDNA methyltransferase 1
- Target synonymsADCADN; AIM; CXXC9; CXXC-type zinc finger protein 9; DNA (cytosine-5-)-methyltransferase 1; DNA (cytosine-5)-methyltransferase 1; DNA methyltransferase HsaI; DNA MTase HsaI; DNMT; HSN1E; m.HsaI; MCMT
- HostRabbit
- IsotypeIgG
- Protein IDP26358
- Protein NameDNA (cytosine-5)-methyltransferase 1
- Scientific DescriptionDNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Host DNA Demethylation Induced by DNMT1 Inhibition Up-Regulates Antiviral OASL Protein during Influenza a Virus Infection.Read more
- Loss of MEG3 contributes to the enhanced migration and invasion in arsenic-induced carcinogenesis through NQO1/FSCN1 pathway.Read more
- The downregulation of miR-509-3p expression by collagen type XI alpha 1-regulated hypermethylation facilitates cancer progression and chemoresistance via the DNA methyltransferase 1/Small ubiquitin-like modifier-3 axis in ovarian cancer cells.Read more
- E3 ubiquitin ligase RNF180 prevents excessive PCDH10 methylation to suppress the proliferation and metastasis of gastric cancer cells by promoting ubiquitination of DNMT1.Read more
- The Downregulation of miR-509-3p Expression by Collagen Type XI Alpha 1-Regulated Hypermethylation Facilitates Cancer Progression and Chemoresistance via the DNA Methyltransferase 1/Small Ubiquitin-like Modifier-3 Axis in Ovarian Cancer Cells.Read more
- LncRNA TINCR impairs the efficacy of immunotherapy against breast cancer by recruiting DNMT1 and downregulating MiR-199a-5p via the STAT1-TINCR-USP20-PD-L1 axis.Read more
- Large-scale DNA demethylation occurs in proliferating ovarian granulosa cells during mouse follicular development. Kawai T et al., 2021 Nov 25, Commun BiolRead more
- Epigenetic regulation by DNA methyltransferases during torpor in the thirteen-lined ground squirrel Ictidomys tridecemlineatus. Tessier SN et al., 2021 Nov, Mol Cell BiochemRead more
- LncRNA TINCR favors tumorigenesis via STAT3-TINCR-EGFR-feedback loop by recruiting DNMT1 and acting as a competing endogenous RNA in human breast cancer. Wang Q et al., 2021 Jan 14, Cell Death DisRead more
- Thioguanine Induces Apoptosis in Triple-Negative Breast Cancer by Regulating PI3K-AKT Pathway. Zhang D et al., 2020, Front OncolRead more
Datasheet
Related products
Product group Antibodies
Anti-Dnmt1 Antibody144-05495
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
TargetDNMT1
- SizePrice
Product group Antibodies
DNMT1 antibodyGTX64361
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
TargetDNMT1
- SizePrice
![IHC-P anaylsis of human placenta tissue using GTX02546 DNMT1 antibody [DNMT1/2061].](https://www.genetex.com/upload/website/prouct_img/normal/GTX02546/GTX02546_20200903_IHC-P_102_w_23053122_190.webp)
Product group Antibodies
DNMT1 antibody [DNMT1/2061]GTX02546
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetDNMT1
- SizePrice
![FACS (Intracellular staining) analysis of HeLa cells using GTX48548 DNMT1 antibody [60B1220.1]. Blue : Primary antibody Orange : isotype control Fixation : 4% PFA](https://www.genetex.com/upload/website/prouct_img/normal/GTX48548/GTX48548_110_FACS_w_23060823_287.webp)
Product group Antibodies
DNMT1 antibody [60B1220.1]GTX48548
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Mass Spectrometry, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetDNMT1
- SizePrice
Product group Antibodies
DNMT1 antibodyGTX11891
ApplicationsImmunoPrecipitation, Western Blot, Other Application
TargetDNMT1
- SizePrice
Product group Antibodies
DNMT1 antibody, InternalGTX88801
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetDNMT1
- SizePrice
Product group Antibodies
ApplicationsImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetDNMT1
- SizePrice
Product group Antibodies
Goat anti-DNMT1EB08317
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
TargetDNMT1
- SizePrice
Product group Antibodies
ApplicationsWestern Blot
TargetDNMT1
- SizePrice