Western blot analysis of extracts of various cell lines using DNMT3B Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using DNMT3B Polyclonal Antibody at dilution of 1:1000.
DNMT3B Polyclonal Antibody
E-AB-60798
Product group Antibodies
Overview
- SupplierElabscience
- Product NameDNMT3B Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionCpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
- UNSPSC12352203