Western blot of 20 ug of human adrenal medulla lysate showing specific immunolabeling of the ~75k DBH protein using Dopamine @-Hydroxylase antibody, C-Term (GTX82708).
Western blot of 20 ug of human adrenal medulla lysate showing specific immunolabeling of the ~75k DBH protein using Dopamine @-Hydroxylase antibody, C-Term (GTX82708).
Dopamine beta Hydroxylase antibody, C-Term
GTX82708
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Primate
TargetDBH
Overview
- SupplierGeneTex
- Product NameDopamine beta Hydroxylase antibody, C-Term
- Delivery Days Customer9
- Application Supplier NoteOptimal working dilutions should be determined experimentally by the end user.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1621
- Target nameDBH
- Target descriptiondopamine beta-hydroxylase
- Target synonymsDBM; dopamine beta-hydroxylase; dopamine beta-hydroxylase (dopamine beta-monooxygenase); ORTHYP1
- HostSheep
- IsotypeIgG
- Protein IDP09172
- Protein NameDopamine beta-hydroxylase
- Scientific DescriptionThe protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse, Primate
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203