![Dopamine Receptor D1 antibody [C2C3], C-term detects Dopamine Receptor D1 protein by immunohistochemical analysis. Sample: Frozen-sectioned mouse cerebral cortex. Green: Dopamine Receptor D1 stained by Dopamine Receptor D1 antibody [C2C3], C-term (GTX100354) diluted at 1:250. Blue: Fluoroshield with DAPI (GTX30920). Dopamine Receptor D1 antibody [C2C3], C-term detects Dopamine Receptor D1 protein by immunohistochemical analysis. Sample: Frozen-sectioned mouse cerebral cortex. Green: Dopamine Receptor D1 stained by Dopamine Receptor D1 antibody [C2C3], C-term (GTX100354) diluted at 1:250. Blue: Fluoroshield with DAPI (GTX30920).](https://www.genetex.com/upload/website/prouct_img/normal/GTX100354/GTX100354_39609_20190509_IHC-Fr_M_w_23060100_757.webp)
Dopamine Receptor D1 antibody [C2C3], C-term detects Dopamine Receptor D1 protein by immunohistochemical analysis. Sample: Frozen-sectioned mouse cerebral cortex. Green: Dopamine Receptor D1 stained by Dopamine Receptor D1 antibody [C2C3], C-term (GTX100354) diluted at 1:250. Blue: Fluoroshield with DAPI (GTX30920).
Dopamine Receptor D1 antibody [C2C3], C-term
GTX100354
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDRD1
Overview
- SupplierGeneTex
- Product NameDopamine Receptor D1 antibody [C2C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration2 mg/ml
- ConjugateUnconjugated
- Gene ID1812
- Target nameDRD1
- Target descriptiondopamine receptor D1
- Target synonymsD1R, DADR, DRD1A, D(1A) dopamine receptor, dopamine D1 receptor
- HostRabbit
- IsotypeIgG
- Protein IDP21728
- Protein NameD(1A) dopamine receptor
- Scientific DescriptionThis gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Li H, Sun F, Bai S, et al. The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice. Int J Mol Med. 2022,49(1):pii: 7. doi: 10.3892/ijmm.2021.5062.Read this paper
- Tapia E, García-Arroyo F, Silverio O, et al. Mycophenolate mofetil and curcumin provide comparable therapeutic benefit in experimental chronic kidney disease: role of Nrf2-Keap1 and renal dopamine pathways. Free Radic Res. 2016,50(7):781-92. doi: 10.1080/10715762.2016.1174776Read this paper

![Dopamine Receptor D1 antibody [C2C3], C-term detects Dopamine Receptor D1 protein by immunofluorescent analysis. Sample: DIV10 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Dopamine Receptor D1 stained by Dopamine Receptor D1 antibody [C2C3], C-term (GTX100354) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody [GT11710] (GTX631836) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920). Dopamine Receptor D1 antibody [C2C3], C-term detects Dopamine Receptor D1 protein by immunofluorescent analysis. Sample: DIV10 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Dopamine Receptor D1 stained by Dopamine Receptor D1 antibody [C2C3], C-term (GTX100354) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody [GT11710] (GTX631836) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920).](https://www.genetex.com/upload/website/prouct_img/normal/GTX100354/GTX100354_39609_20181227_ICC_IF_R_w_23060100_553.webp)
![Dopamine Receptor D1 antibody [C2C3], C-term detects Dopamine Receptor D1 protein by immunofluorescent analysis. Sample: Mock and transfected 293T cells were fixed in ice-cold MeOH for 5 min. Green: Dopamine Receptor D1 stained by Dopamine Receptor D1 antibody [C2C3], C-term (GTX100354) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920). Dopamine Receptor D1 antibody [C2C3], C-term detects Dopamine Receptor D1 protein by immunofluorescent analysis. Sample: Mock and transfected 293T cells were fixed in ice-cold MeOH for 5 min. Green: Dopamine Receptor D1 stained by Dopamine Receptor D1 antibody [C2C3], C-term (GTX100354) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920).](https://www.genetex.com/upload/website/prouct_img/normal/GTX100354/GTX100354_39609_20240927_ICC_IF_B_24100318_597.webp)




![Mouse tissue extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with Dopamine Receptor D1 antibody [HL2553] (GTX638925) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX638925/GTX638925_45313_20250124_WB_M_brain_25020422_962.webp)
![Non-transfected (–) and transfected (+) unboiled 293T whole cell extracts were separated by 10% SDS-PAGE, and the membrane was blotted with Dopamine Receptor D1 antibody [HL2680] (GTX639344) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639344/GTX639344_T-45222_20240216_WB_multiple_B_24021917_587.webp)
![Dopamine Receptor D1 antibody [HL2927] detects Dopamine Receptor D1 protein by immunofluorescent analysis. Sample: Mock and transfected 293T cells were fixed in ice-cold MeOH for 5 min. Green: Dopamine Receptor D1 stained by Dopamine Receptor D1 antibody [HL2927] (GTX640270) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920).](https://www.genetex.com/upload/website/prouct_img/normal/GTX640270/GTX640270_T-45390_20240510_ICC_IF_B_24070822_338.webp)