Doramapimod (GMP)
HY-10320G
CAS Number285983-48-4
Product group Chemicals
Molecular Weight527.66
Overview
- SupplierMedChem Express
- Product NameDoramapimod (GMP)
- Delivery Days Customer5
- CAS Number285983-48-4
- CertificationResearch Use Only
- Molecular FormulaC31H37N5O3
- Molecular Weight527.66
- Scientific DescriptionDoramapimod GMP (BIRB 796 GMP) is an orally active inhibitor for p38 MAPK, with IC50s of 38, 65, 200 and 520 nM, for p38alpha, p38beta, p38gamma, p38delta. Doramapimod exhibits cytotoxicity and antitumor activity against multiple myeloma, synergizes with multidrug resistance protein 1 (ABCB1) and aurora kinase inhibitor VX680, promoting their antitumor efficacy against oral epidermoid carcinoma and cervical cancer. Doramapimod also exhibits anti-inflammatory activity[1].
- SMILESO=C(NC1=CC(C(C)(C)C)=NN1C2=CC=C(C)C=C2)NC3=C4C=CC=CC4=C(OCCN5CCOCC5)C=C3
- UNSPSC12352200
MSDS
Related products
Product group Chemicals
Doramapimod27034
CAS Number285983-48-4
Estimated Purity≥98%
Molecular Weight527.7 Da
- SizePrice
Product group Chemicals
DoramapimodHY-10320
CAS Number285983-48-4
Estimated Purity99.98
Molecular Weight527.66
- SizePrice
Product group Chemicals
Doramapimod [285983-48-4]M39-900
CAS Number285983-48-4
Estimated Purity>98%
Molecular Weight527.7
- SizePrice
![Doramapimod [285983-48-4]](https://www.targetmol.com/group3/M00/35/47/CgoaEGayGqOEYeypAAAAAKTDVcU071.png)
Product group Chemicals
CAS Number285983-48-4
Estimated Purity99.65%
Molecular Weight527.66
- SizePrice
Product group Chemicals
BIRB796M1675
CAS Number285983-48-4
Estimated Purity0.99
Molecular Weight527.66
- SizePrice
Product group Chemicals
DoramapimodORB1300911
CAS Number285983-48-4
Estimated Purity99.65%
Molecular Weight527.66
- SizePrice