3 microg of GTX66972-pro Human DR5 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
3 microg of GTX66972-pro Human DR5 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
Human DR5 protein, human IgG1 Fc and His tag (active)
GTX66972-PRO
ApplicationsFunctional Assay
Product group Proteins / Signaling Molecules
Protein IDO14763
Overview
- SupplierGeneTex
- Product NameHuman DR5 protein (active)
- Delivery Days Customer9
- Application Supplier NoteMeasured by its ability to inhibit cytotoxicity assay using Jurkat human T lymphocyte. The ED50 for this effect less or equal to 5 ng/ml with TRAIL.
- ApplicationsFunctional Assay
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Protein IDO14763
- Protein NameTumor necrosis factor receptor superfamily member 10B
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352202