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Western blot analysis of extracts of Mouse heart using DROSHA Polyclonal Antibody at 1:500 dilution.
Western blot analysis of extracts of Mouse heart using DROSHA Polyclonal Antibody at 1:500 dilution.
Western blot analysis of extracts of Mouse heart using DROSHA Polyclonal Antibody at 1:500 dilution.

DROSHA Polyclonal Antibody

E-AB-62428
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    DROSHA Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.
  • UNSPSC
    12352203