WB analysis of various samples using GTX57630 DUSP3 antibody. Lane 1 : HeLa whole cell lysate Lane 2 : HepG2 whole cell lysate Lane 3 : Jurkat whole cell lysate Lane 4 : MCF-7 whole cell lysate Lane 5 : 293T whole cell lysate Lane 6 : U87-MG whole cell lysate Lane 7 : K562 whole cell lysate Loading : 40 microg Dilution : 1:3000
WB analysis of various samples using GTX57630 DUSP3 antibody. Lane 1 : HeLa whole cell lysate Lane 2 : HepG2 whole cell lysate Lane 3 : Jurkat whole cell lysate Lane 4 : MCF-7 whole cell lysate Lane 5 : 293T whole cell lysate Lane 6 : U87-MG whole cell lysate Lane 7 : K562 whole cell lysate Loading : 40 microg Dilution : 1:3000
DUSP3 antibody [AT9E6]
GTX57630
Overview
- SupplierGeneTex
- Product NameDUSP3 antibody [AT9E6]
- Delivery Days Customer9
- Application Supplier NoteWB: Recommended starting dilution is 1:3000.. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDAT9E6
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1845
- Target nameDUSP3
- Target descriptiondual specificity phosphatase 3
- Target synonymsdual specificity protein phosphatase 3; dual specificity protein phosphatase VHR; serine/threonine specific protein phosphatase; vaccinia H1-related phosphatase; vaccinia virus phosphatase VH1-related; VHR
- HostMouse
- IsotypeIgG2b
- Protein IDP51452
- Protein NameDual specificity protein phosphatase 3
- Scientific DescriptionThe protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203