Dystrophin antibody [Dy8/6C5]

GeneTex

Dystrophin antibody [Dy8/6C5]

9

This antibody reacts strongly with the carboxy terminus (between amino acids 3669 and 3685) of human dystrophin.No cross-reactivity with mdx mouse tissue. Cross reacts very weakly with pig dystrophin.

ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

Dy8/6C5

Unconjugated

DMD

dystrophin

BMD; CMD3B; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; dystrophin; MRX85; truncated dystrophin

Mouse

IgG1

This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]

Canine, Chicken, Hamster, Human, Mouse, Rabbit, Rat

2°C to 8°C,-20°C or -80°C

12352203