FACS analysis of MCF-7 cells using GTX02618 E-Cadherin antibody [CDH1/2208R]. Blue : Primary antibody Red : Isotype control
E-Cadherin antibody [CDH1/2208R]
GTX02618
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCDH1
Overview
- SupplierGeneTex
- Product NameE-Cadherin antibody [CDH1/2208R]
- Delivery Days Customer9
- Antibody SpecificityWe do not recommend use of this product for Mouse,Rat.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCDH1/2208R
- Concentration200 ug/ml
- ConjugateUnconjugated
- Gene ID999
- Target nameCDH1
- Target descriptioncadherin 1
- Target synonymsArc-1; BCDS1; cadherin 1, E-cadherin (epithelial); cadherin 1, type 1, E-cadherin (epithelial); cadherin-1; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDHE; cell-CAM 120/80; ECAD; E-cadherin 1; epididymis secretory sperm binding protein; epithelial cadherin; LCAM; UVO; uvomorulin
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203