![IHC-P analysis of human invasive breast cancer of no special type (NST) tissue using GTX04367 E-Cadherin antibody [MSVA-035R] HistoMAX?. Strong membranous E-Cadherin staining in a breast cancer NST. IHC-P analysis of human invasive breast cancer of no special type (NST) tissue using GTX04367 E-Cadherin antibody [MSVA-035R] HistoMAX?. Strong membranous E-Cadherin staining in a breast cancer NST.](https://www.genetex.com/upload/website/prouct_img/normal/GTX04367/GTX04367_20230728_IHC-P_48_23072722_741.webp)
IHC-P analysis of human invasive breast cancer of no special type (NST) tissue using GTX04367 E-Cadherin antibody [MSVA-035R] HistoMAX?. Strong membranous E-Cadherin staining in a breast cancer NST.
E-Cadherin antibody [MSVA-035R] HistoMAX(tm)
GTX04367
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCDH1
Overview
- SupplierGeneTex
- Product NameE-Cadherin antibody [MSVA-035R] HistoMAX(tm)
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMSVA-035R
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID999
- Target nameCDH1
- Target descriptioncadherin 1
- Target synonymsArc-1, BCDS1, CD324, CDHE, ECAD, LCAM, UVO, cadherin-1, CAM 120/80, E-cadherin 1, cadherin 1, E-cadherin (epithelial), cadherin 1, type 1, E-cadherin (epithelial), calcium-dependent adhesion protein, epithelial, cell-CAM 120/80, epididymis secretory sperm binding protein, epithelial cadherin, uvomorulin
- HostRabbit
- IsotypeIgG
- Protein IDP12830
- Protein NameCadherin-1
- Scientific DescriptionThis gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
![IHC-P analysis of human invasive lobular breast cancer (ILC) tissue using GTX04367 E-Cadherin antibody [MSVA-035R] HistoMAX?. Absence of E-Cadherin staining in an invasive lobular breast cancer while normal breast glands show strong E cadherin positivity. IHC-P analysis of human invasive lobular breast cancer (ILC) tissue using GTX04367 E-Cadherin antibody [MSVA-035R] HistoMAX?. Absence of E-Cadherin staining in an invasive lobular breast cancer while normal breast glands show strong E cadherin positivity.](https://www.genetex.com/upload/website/prouct_img/normal/GTX04367/GTX04367_20230728_IHC-P_178_23072723_456.webp)
![IHC-P analysis of human invasive lobular breast cancer (ILC) tissue using GTX04367 E-Cadherin antibody [MSVA-035R] HistoMAX?. Absence of E-Cadherin staining in a lobular breast cancer. IHC-P analysis of human invasive lobular breast cancer (ILC) tissue using GTX04367 E-Cadherin antibody [MSVA-035R] HistoMAX?. Absence of E-Cadherin staining in a lobular breast cancer.](https://www.genetex.com/upload/website/prouct_img/normal/GTX04367/GTX04367_20230728_IHC-P_308_23072723_639.webp)




![FACS analysis of MCF-7 cells using GTX02618 E-Cadherin antibody [CDH1/2208R]. Blue : Primary antibody Red : Isotype control](https://www.genetex.com/upload/website/prouct_img/normal/GTX02618/GTX02618_20210319_FACS_w_23053122_361.webp)
![IHC-P analysis of human breast tissue using GTX57174 E-cadherin antibody [IHC564] (10X)](https://www.genetex.com/upload/website/prouct_img/normal/GTX57174/GTX57174_20180619_IHC-P_w_23061123_877.webp)
![E-Cadherin antibody [GT477] detects E-Cadherin protein at cell membrane and cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded dog skin. E-Cadherin stained by E-Cadherin antibody [GT477] (GTX629691) diluted at 1:200. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX629691/GTX629691_41400_20190215_IHC-P_D_22111423_557.webp)
![E-Cadherin antibody [GT311] (GTX629692) detects E-Cadherin protein by flow cytometry analysis. Sample: MCF-7 cell. Black: Unlabelled sample was used as a control. Red: E-Cadherin antibody [GT311] (GTX629692) dilution: 1:50. Acquisition of 20,000 events were collected for FACS analysis.](https://www.genetex.com/upload/website/prouct_img/normal/GTX629692/GTX629692_41400_20181207_FACS_w_23061202_932.webp)