Western Blot Positive WB detected in: Jurkat whole cell lysate, PC-3 whole cell lysate, Rat Heart tissue All lanes: E2F1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 47 kDa Observed band size: 60 kDa
Western Blot Positive WB detected in: Jurkat whole cell lysate, PC-3 whole cell lysate, Rat Heart tissue All lanes: E2F1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 47 kDa Observed band size: 60 kDa
E2F1 Recombinant Monoclonal Antibody
CSB-RA826096A0HU
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetE2F1
Overview
- SupplierCusabio
- Product NameE2F1 Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1D12
- ConjugateUnconjugated
- Gene ID1869
- Target nameE2F1
- Target descriptionE2F transcription factor 1
- Target synonymsE2F-1; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; retinoblastoma-associated protein 1; retinoblastoma-binding protein 3; transcription factor E2F1
- IsotypeIgG
- Protein IDQ01094
- Protein NameTranscription factor E2F1
- Scientific DescriptionTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5-TTTC[CG]CGC-3 found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203