ProductsBack/E2F1 Recombinant Monoclonal Antibody

Western Blot Positive WB detected in: Jurkat whole cell lysate, PC-3 whole cell lysate, Rat Heart tissue All lanes: E2F1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 47 kDa Observed band size: 60 kDa

E2F1 Recombinant Monoclonal Antibody

Name: E2F1 Recombinant Monoclonal Antibody
SKU: CSB-RA826096A0HU_C90
Availability: BackOrder

CSB-RA826096A0HU

ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

TargetE2F1

Overview

Supplier
Cusabio
Product Name
E2F1 Recombinant Monoclonal Antibody
Delivery Days Customer
20
Applications
Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
1D12
Conjugate
Unconjugated
Gene ID1869
Target name
E2F1
Target description
E2F transcription factor 1
Target synonyms
E2F-1; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; retinoblastoma-associated protein 1; retinoblastoma-binding protein 3; transcription factor E2F1
Isotype
IgG
Protein IDQ01094
Protein Name
Transcription factor E2F1
Scientific Description
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5-TTTC[CG]CGC-3 found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812).
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

E2F1 Recombinant Monoclonal Antibody

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Overview

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