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IHC-P analysis of human, vascular endothelium tissue using GTX77919 EDG1 antibody.
IHC-P analysis of human, vascular endothelium tissue using GTX77919 EDG1 antibody.
IHC-P analysis of human, vascular endothelium tissue using GTX77919 EDG1 antibody.

EDG1 antibody

GTX77919
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetS1PR1
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Overview

  • Supplier
    GeneTex
  • Product Name
    EDG1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 3 - 6 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1901
  • Target name
    S1PR1
  • Target description
    sphingosine-1-phosphate receptor 1
  • Target synonyms
    CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1, sphingosine 1-phosphate receptor 1, S1P receptor Edg-1, endothelial differentiation G-protein coupled receptor 1, endothelial differentiation, sphingolipid G-protein-coupled receptor, 1, sphingosine 1-phosphate receptor EDG1, sphingosine 1-phosphate receptor Edg-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP21453
  • Protein Name
    Sphingosine 1-phosphate receptor 1
  • Scientific Description
    The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Mourad-Zeidan AA, Melnikova VO, Wang H, et al. Expression profiling of Galectin-3-depleted melanoma cells reveals its major role in melanoma cell plasticity and vasculogenic mimicry. Am J Pathol. 2008,173(6):1839-52. doi: 10.2353/ajpath.2008.080380
    Read this paper