EED antibody

GeneTex

EED antibody

9

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

EED

embryonic ectoderm development

COGIS; embryonic ectoderm development protein; HEED; polycomb protein EED; WAIT1; WD protein associating with integrin cytoplasmic tails 1

Chicken

IgY

Polycomb protein EED

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Four transcript variants encoding distinct isoforms have been identified for this gene. The four isoforms are differentialy expressed during ES cell differentiation, with four isoforms intially expressed. Only isoform 3 then remains after differentiation.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203