EIF6 antibody

GeneTex

EIF6 antibody

7

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

EIF6

eukaryotic translation initiation factor 6

b(2)gcn; B4 integrin interactor; CAB; EIF3A; eIF-6; eukaryotic translation initiation factor 3A; eukaryotic translation initiation factor 6; ITGB4BP; p27 beta-4 integrin-binding protein; p27(BBP); p27BBP

Rabbit

IgG

Eukaryotic translation initiation factor 6

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

Human

-20°C or -80°C,2°C to 8°C

12352203