ELAVL1 / HuR antibody [GT1182] - Recombinant antibody, KO/KD Validated

GeneTex

ELAVL1 / HuR antibody [GT1182] - Recombinant antibody, KO/KD Validated

9

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

GT1182

Unconjugated

ELAVL1

ELAV like RNA binding protein 1

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); ELAV1; ELAV-like protein 1; embryonic lethal, abnormal vision, drosophila, homolog-like 1; Hu antigen R; Hua; hu-antigen R; HUR; MelG

Rabbit

IgG

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3 untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]

Human, Mouse, Rat

2°C to 8°C,-20°C or -80°C

12352203