EpCAM antibody [N3C3]
GTX113091
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetEPCAM
Overview
- SupplierGeneTex
- Product NameEpCAM antibody [N3C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.3 mg/ml
- ConjugateUnconjugated
- Gene ID4072
- Target nameEPCAM
- Target descriptionepithelial cell adhesion molecule
- Target synonymsBer-Ep4, BerEp4, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, LYNCH8, M4S1, MIC18, MK-1, MOC-31, TACSTD1, TROP1, epithelial cell adhesion molecule, adenocarcinoma-associated antigen, cell surface glycoprotein Trop-1, epithelial glycoprotein 314, human epithelial glycoprotein-2, major gastrointestinal tumor-associated protein GA733-2, membrane component, chromosome 4, surface marker (35kD glycoprotein), trophoblast cell surface antigen 1, tumor-associated calcium signal transducer 1
- HostRabbit
- IsotypeIgG
- Protein IDP16422
- Protein NameEpithelial cell adhesion molecule
- Scientific DescriptionThis gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Zhang K, Wang J, Yang L, et al. Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer. Mol Cancer. 2018,17(1):153. doi: 10.1186/s12943-018-0896-8Read this paper
- Lee YH, Jhuang YL, Chen YL, et al. Paradoxical overexpression of MBNL2 in hepatocellular carcinoma inhibits tumor growth and invasion. Oncotarget. 2016,7(40):65589-65601. doi: 10.18632/oncotarget.11577Read this paper
- Sridaran D, Ramamoorthi G, MahaboobKhan R, et al. Oxystressed tumor microenvironment potentiates epithelial to mesenchymal transition and alters cellular bioenergetics towards cancer progression. Tumour Biol. 2016,37(10):13307-13322.Read this paper
- Al-Lamki RS, Wang J, Yang J, et al. Tumor necrosis factor receptor 2-signaling in CD133-expressing cells in renal clear cell carcinoma. Oncotarget. 2016,7(17):24111-24. doi: 10.18632/oncotarget.8125Read this paper






![FACS analysis of MCF-7 cells using GTX00606-07 EpCAM antibody [VU-1D9] (APC).](https://www.genetex.com/upload/website/prouct_img/normal/GTX00606-07/GTX00606-07_20191025_AP_006_105_w_23053121_233.webp)