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EpCAM antibody [VU-1D9] (Biotin)

Research Use Only
GTX72682
GeneTex
ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetEPCAM
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Overview

  • Supplier
    GeneTex
  • Product Name
    EpCAM antibody [VU-1D9] (Biotin)
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    VU-1D9
  • Conjugate
    Biotin
  • Formulation
    Liquid
  • Gene ID4072
  • Target name
    EPCAM
  • Target description
    epithelial cell adhesion molecule
  • Target synonyms
    adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; DIAR5; EGP-2; EGP314; EGP40; epithelial cell adhesion molecule; epithelial glycoprotein 314; ESA; HNPCC8; human epithelial glycoprotein-2; KS1/4; KSA; M4S1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; TACSTD1; TROP1; trophoblast cell surface antigen 1; tumor-associated calcium signal transducer 1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP16422
  • Protein Name
    Epithelial cell adhesion molecule
  • Scientific Description
    This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk. Twigger AJ et al., 2022 Jan 28, Nat Commun
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  • Virtual-freezing fluorescence imaging flow cytometry. Mikami H et al., 2020 Mar 6, Nat Commun
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  • Optimisation of immunofluorescence methods to determine MCT1 and MCT4 expression in circulating tumour cells. Kershaw S et al., 2015 May 10, BMC Cancer
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  • Mutational analysis of circulating tumor cells from colorectal cancer patients and correlation with primary tumor tissue. Lyberopoulou A et al., 2015, PLoS One
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  • High-purity separation of cancer cells by optically induced dielectrophoresis. Chen HH et al., 2014 Apr, J Biomed Opt
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  • Hyaluronan synthase HAS2 promotes tumor progression in bone by stimulating the interaction of breast cancer stem-like cells with macrophages and stromal cells. Okuda H et al., 2012 Jan 15, Cancer Res
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  • Characterization of the epithelial cell adhesion molecule (EpCAM)+ cell population in hepatocellular carcinoma cell lines. Kimura O et al., 2010 Oct, Cancer Sci
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