
WB analysis of human brain lysate using GTX48613 ERAB antibody. Dilution : 0.3microg/ml Loading : 30microg protein in RIPA buffer
ERAB antibody
GTX48613
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Zebra Fish
TargetHSD17B10
Overview
- SupplierGeneTex
- Product NameERAB antibody
- Delivery Days Customer9
- Antibody SpecificityThis antibody is expected to recognise both reported isoforms.
- Application Supplier NoteWB: 0.3-2microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID3028
- Target nameHSD17B10
- Target descriptionhydroxysteroid 17-beta dehydrogenase 10
- Target synonyms17b-HSD10; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type-2; ABAD; AB-binding alcohol dehydrogenase; amyloid-beta peptide binding alcohol dehydrogenase; CAMR; DUPXp11.22; endoplasmic reticulum-associated amyloid beta-peptide-binding protein; ERAB; HADH2; HCD2; HSD10MD; MHBD; mitochondrial ribonuclease P protein 2; mitochondrial RNase P subunit 2; MRPP2; MRX17; MRX31; MRXS10; SCHAD; SDR5C1; short chain L-3-hydroxyacyl-CoA dehydrogenase type 2; short chain type dehydrogenase/reductase XH98G2
- HostGoat
- IsotypeIgG
- Protein IDQ99714
- Protein Name3-hydroxyacyl-CoA dehydrogenase type-2
- Scientific DescriptionThis gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014]
- ReactivityHuman, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Sex-dependent effects of microcystin-LR on hypothalamic-pituitary-gonad axis and gametogenesis of adult zebrafish. Liu W et al., 2016 Mar 10, Sci RepRead more