ERp57 antibody [C3], C-term
GTX100297
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPDIA3
Overview
- SupplierGeneTex
- Product NameERp57 antibody [C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2923
- Target namePDIA3
- Target descriptionprotein disulfide isomerase family A member 3
- Target synonyms58 kDa glucose-regulated protein; 58 kDa microsomal protein; disulfide isomerase ER-60; endoplasmic reticulum P58; endoplasmic reticulum resident protein 57; endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER protein 57; ER protein 60; ER60; ERp57; ERp60; ERp61; glucose regulated protein, 58kDa; GRP57; GRP58; HEL-S-269; HEL-S-93n; HsT17083; P58; phospholipase C-alpha; PI-PLC; protein disulfide isomerase-associated 3; protein disulfide-isomerase A3
- HostRabbit
- IsotypeIgG
- Protein IDP30101
- Protein NameProtein disulfide-isomerase A3
- Scientific DescriptionThis gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Characterization of the endoplasmic reticulum-resident peroxidases GPx7 and GPx8 shows the higher oxidative activity of GPx7 and its linkage to oxidative protein folding. Kanemura S et al., 2020 Sep 4, J Biol ChemRead more
- Intracellular mannose binding lectin mediates subcellular trafficking of HIV-1 gp120 in neurons. Teodorof C et al., 2014 Sep, Neurobiol DisRead more
- Identification of the proteins required for fatty acid desaturation in zebrafish (Danio rerio). Chen YS et al., 2013 Nov 1, Biochem Biophys Res CommunRead more