Estrogen Receptor beta antibody [6B12]
GTX70180
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetESR2
Overview
- SupplierGeneTex
- Product NameEstrogen Receptor beta antibody [6B12]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID6B12
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2100
- Target nameESR2
- Target descriptionestrogen receptor 2
- Target synonymsER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2, ODG8, estrogen receptor beta, estrogen receptor beta 2, estrogen receptor beta 4, nuclear receptor subfamily 3 group A member 2, oestrogen receptor beta
- HostMouse
- IsotypeIgG1
- Protein IDQ92731
- Protein NameEstrogen receptor beta
- Scientific DescriptionThis gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Dietrich W, Gaba A, Zhegu Z, et al. Testosterone dependent androgen receptor stabilization and activation of cell proliferation in primary human myometrial microvascular endothelial cells. Fertil Steril. 2011,95(4):1247-55.e1-2. doi: 10.1016/j.fertnstert.2010.11.012Read this paper
- Demyanets S, Pfaffenberger S, Kaun C, et al. The estrogen metabolite 17beta-dihydroequilenin counteracts interleukin-1alpha induced expression of inflammatory mediators in human endothelial cells in vitro via NF-kappaB pathway. Thromb Haemost. 2006,95(1):107-16.Read this paper
- Tschugguel W, Dietrich W, Zhegu Z, et al. Differential regulation of proteasome-dependent estrogen receptor alpha and beta turnover in cultured human uterine artery endothelial cells. J Clin Endocrinol Metab. 2003,88(5):2281-7.Read this paper
- Fuchsjäger-Mayrl G, Nepp J, Schneeberger C, et al. Identification of estrogen and progesterone receptor mRNA expression in the conjunctiva of premenopausal women. Invest Ophthalmol Vis Sci. 2002,43(9):2841-4.Read this paper




