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FACS analysis of 293 cells using GTX80605 Factor B antibody, Internal. Green : primary antibody Blue : negative control
FACS analysis of 293 cells using GTX80605 Factor B antibody, Internal. Green : primary antibody Blue : negative control
FACS analysis of 293 cells using GTX80605 Factor B antibody, Internal. Green : primary antibody Blue : negative control

Factor B (Bb fragment) antibody, Internal

GTX80605
GeneTex
TargetCFB
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    Factor B antibody, Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. IHC-P: 1:50-1:100. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Formulation
    Liquid
  • Gene ID629
  • Target name
    CFB
  • Target description
    complement factor B
  • Target synonyms
    AHUS4; ARMD14; BF; B-factor, properdin; BFD; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFBD; complement factor B; FB; FBI12; GBG; glycine-rich beta-glycoprotein; H2-Bf; PBF2; properdin factor B
  • Protein IDP00751
  • Protein Name
    Complement factor B
  • Scientific Description
    This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5 end of the gene for complement component 2. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203