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The data was published in the journal Evid Based Complement Alternat Med in 2012.PMID: 23320038
The data was published in the journal Evid Based Complement Alternat Med in 2012.PMID: 23320038
The data was published in the journal Evid Based Complement Alternat Med in 2012.PMID: 23320038

FAK (phospho Tyr397) antibody

GTX24803
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityAmphibian, Canine, Chicken, Drosophila, Feline, Fish, Human, Mouse, Primate, Rat, Xenopus, Zebra Fish
TargetPTK2
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Overview

  • Supplier
    GeneTex
  • Product Name
    FAK (phospho Tyr397) antibody - Orthogonal Validated
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID5747
  • Target name
    PTK2
  • Target description
    protein tyrosine kinase 2
  • Target synonyms
    FADK; FADK 1; FAK; FAK1; FAK-related non-kinase polypeptide; focal adhesion kinase 1; focal adhesion kinase-related nonkinase; FRNK; p125FAK; pp125FAK; PPP1R71; protein phosphatase 1 regulatory subunit 71; PTK2 protein tyrosine kinase 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ05397
  • Protein Name
    Focal adhesion kinase 1
  • Scientific Description
    This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
  • Reactivity
    Amphibian, Canine, Chicken, Drosophila, Feline, Fish, Human, Mouse, Primate, Rat, Xenopus, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The Physical Role of Mesenchymal Cells Driven by the Actin Cytoskeleton Is Essential for the Orientation of Collagen Fibrils in Zebrafish Fins. Kuroda J et al., 2020, Front Cell Dev Biol
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  • Glycine and succinic acid are effective indicators of the suppression of epithelial-mesenchymal transition by fucoxanthinol in colorectal cancer stem-like cells. Terasaki M et al., 2018 Jul, Oncol Rep
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  • Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Liu CC et al., 2016 Jun 16, Nat Commun
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  • Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-beta. McAndrews KM et al., 2015 Nov 20, Sci Rep
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  • Alterations in ovarian cancer cell adhesion drive taxol resistance by increasing microtubule dynamics in a FAK-dependent manner. McGrail DJ et al., 2015 Apr 17, Sci Rep
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  • Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells. Hsu HY et al., 2012, Evid Based Complement Alternat Med
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