Bio-Connect
ICC/IF analysis of HeLa cells using GTX24803 FAK (phospho Tyr397) antibody. Green : Primary antibody Blue : cell nucleus Fixation/Permeabilization : ice-cold 95% methanol
ICC/IF analysis of HeLa cells using GTX24803 FAK (phospho Tyr397) antibody. Green : Primary antibody Blue : cell nucleus Fixation/Permeabilization : ice-cold 95% methanol
ICC/IF analysis of HeLa cells using GTX24803 FAK (phospho Tyr397) antibody. Green : Primary antibody Blue : cell nucleus Fixation/Permeabilization : ice-cold 95% methanol

FAK (phospho Tyr397) antibody

GTX24803
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityAmphibian, Canine, Chicken, Drosophila, Feline, Fish, Human, Mouse, Primate, Rat, Xenopus, Zebra Fish
TargetPTK2
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    FAK (phospho Tyr397) antibody
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID5747
  • Target name
    PTK2
  • Target description
    protein tyrosine kinase 2
  • Target synonyms
    FADK, FADK 1, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, focal adhesion kinase 1, FAK-related non-kinase polypeptide, PTK2 protein tyrosine kinase 2, focal adhesion kinase-related nonkinase, protein phosphatase 1 regulatory subunit 71
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ05397
  • Protein Name
    Focal adhesion kinase 1
  • Scientific Description
    This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
  • Reactivity
    Amphibian, Canine, Chicken, Drosophila, Feline, Fish, Human, Mouse, Primate, Rat, Xenopus, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Kuroda J, Itabashi T, Iwane AH, et al. The Physical Role of Mesenchymal Cells Driven by the Actin Cytoskeleton Is Essential for the Orientation of Collagen Fibrils in Zebrafish Fins. Front Cell Dev Biol. 2020,8:580520. doi: 10.3389/fcell.2020.580520
    Read this paper
  • Terasaki M, Mima M, Kudoh S, et al. Glycine and succinic acid are effective indicators of the suppression of epithelial-mesenchymal transition by fucoxanthinol in colorectal cancer stem-like cells. Oncol Rep. 2018,40(1):414-424. doi: 10.3892/or.2018.6398
    Read this paper
  • Liu CC, Lin SP, Hsu HS, et al. Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Nat Commun. 2016,7:11798. doi: 10.1038/ncomms11798
    Read this paper
  • McAndrews KM, McGrail DJ, Ravikumar N, et al. Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-β. Sci Rep. 2015,5:16941. doi: 10.1038/srep16941
    Read this paper
  • McGrail DJ, Khambhati NN, Qi MX, et al. Alterations in ovarian cancer cell adhesion drive taxol resistance by increasing microtubule dynamics in a FAK-dependent manner. Sci Rep. 2015,5:9529. doi: 10.1038/srep09529
    Read this paper
  • Hsu HY, Lin JH, Li CJ, et al. Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells. Evid Based Complement Alternat Med. 2012,2012:819632. doi: 10.1155/2012/819632
    Read this paper