
The data was published in the journal Evid Based Complement Alternat Med in 2012.PMID: 23320038
FAK (phospho Tyr397) antibody
GTX24803
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityAmphibian, Canine, Chicken, Drosophila, Feline, Fish, Human, Mouse, Primate, Rat, Xenopus, Zebra Fish
TargetPTK2
Overview
- SupplierGeneTex
- Product NameFAK (phospho Tyr397) antibody - Orthogonal Validated
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5747
- Target namePTK2
- Target descriptionprotein tyrosine kinase 2
- Target synonymsFADK; FADK 1; FAK; FAK1; FAK-related non-kinase polypeptide; focal adhesion kinase 1; focal adhesion kinase-related nonkinase; FRNK; p125FAK; pp125FAK; PPP1R71; protein phosphatase 1 regulatory subunit 71; PTK2 protein tyrosine kinase 2
- HostRabbit
- IsotypeIgG
- Protein IDQ05397
- Protein NameFocal adhesion kinase 1
- Scientific DescriptionThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]
- ReactivityAmphibian, Canine, Chicken, Drosophila, Feline, Fish, Human, Mouse, Primate, Rat, Xenopus, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- The Physical Role of Mesenchymal Cells Driven by the Actin Cytoskeleton Is Essential for the Orientation of Collagen Fibrils in Zebrafish Fins. Kuroda J et al., 2020, Front Cell Dev BiolRead more
- Glycine and succinic acid are effective indicators of the suppression of epithelial-mesenchymal transition by fucoxanthinol in colorectal cancer stem-like cells. Terasaki M et al., 2018 Jul, Oncol RepRead more
- Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Liu CC et al., 2016 Jun 16, Nat CommunRead more
- Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-beta. McAndrews KM et al., 2015 Nov 20, Sci RepRead more
- Alterations in ovarian cancer cell adhesion drive taxol resistance by increasing microtubule dynamics in a FAK-dependent manner. McGrail DJ et al., 2015 Apr 17, Sci RepRead more
- Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells. Hsu HY et al., 2012, Evid Based Complement Alternat MedRead more